The Journal of Physiology and Pharmacology was established in 1950 as an Acta Physiologica Polonica by the Polish Physiological Society. This publication is a international, peer-reviewed scientific journal that publishes original papers, short communications, and reviews dealing with basic and applied physiology, pathophysiology and pharmacology. The Polish Physiological Society publishes it bimonthly in one volume a year, both in printed and electronic format. The printed version is available to subscribers and the full text e-version is provided as open access (www.jpp.krakow.pl). The Journal of Physiology and Pharmacology is indexed in many international databases, for example in Medline, Embase, Scopus and Biosis.

SUBMISSION OF MANUSCRIPTS
The manuscript must be written in English with appropriate figures and/or tables e-mailed to the Journal's Editorial Office located at the Department of Physiology, Jagiellonian University Medical College, 16 Grzegorzecka Street, 31-531 Krakow, Poland; e-mail: redjpp@cm-uj.krakow.pl.

The manuscript should be prepared in two formats:
1. Microsoft Word (.doc) format - the text of the manuscript in Word and with each table and figure sent as a separate file with a minimum resolution of 300 dpi;
2. Adobe Acrobat (.pdf) format - the manuscript with figures and tables mounted as one pdf file.

Authors have also to submit a full version of revised manuscript in two formats (first in Word with figures and tables in separate files and the second format in one pdf file with all figures and tables attached at the end of the text).

The manuscript handling fee is 800 EUR or in Polish currency 3500 PLN and should be sent along with the manuscript submission. The fee is not refundable and is not contingent on acceptance of the paper. Papers accepted by the Journal must not be published elsewhere, without prior written permission of the Editorial Office.

A cover letter must be included and signed by the corresponding author and must state that the data being presented to the journal has not been published elsewhere in whole and in part (except abstract), and that all authors agree to publish the work in the Journal of Physiology and Pharmacology.

There are no restrictions on the length of manuscripts submitted or on the number of figures or tables. Articles should be written clearly, concisely and with the number of figures and tables kept to the minimum necessary to illustrate the hypothesis being tested. However, authors may be asked to reduce the length of the manuscript or the number of figures.

Original papers should contain the following sections in the order listed: title page, summary, key words, introduction, material and methods, results, discussion, acknowledgements (optional) and/or source of funds, a statement regarding conflict of interests, references, and tables and/or figures with legend (optional).

The title page should include the name(s) of the author(s) with initials and the affiliation(s) of the author(s) included in the address of the department or laboratory where the work was performed, and the title of the manuscript. Each author should contribute to writing the paper and take responsibility for a particular section of the study. The title should indicate clearly the subject matter of the paper. If possible, please avoid specialist abbreviations in the titles.

Summary: The paper must include a precise summary with no more than 300 words and should concisely present the hypothesis being tested, the general methods, results and conclusions. References may not be cited in the summary.

Materials and Methods: When conducting experiments on animals, authors should follow the institutions or the National Research Council's guidelines for the care and use of laboratory animals. When conducting scientific research on humans or human tissue, researchers should follow procedures that are in accordance with the ethical standards of the latest revision of the Helsinki Declaration. The Journal of Physiology and Pharmacology requires authors to affirm that original studies reported in the Journal have been carried out in accordance with the Declaration of Helsinki and/or with the guidelines for the care and use of laboratory animals that is accepted by properly appointed Ethics Committees. The editors reserve the right to reject papers if there is doubt as to whether suitable experimental procedures were used.

Lists of materials, chemicals and equipment, and an explanation of procedures may be given as separately headed paragraphs. The details of conducting experiments should be sufficient to allow the work to be repeated by others.

Discussion: The discussion should not merely recapitulate the results. Authors should provide a conclusion to their work and express an opinion on the relevance of the results in the context of other works cited in the paper.

Acknowledgements: The wording of acknowledgements must have been accepted by the persons concerned. Authors should provide the source of their funding.

Disclosure of potential conflicts of interests: Authors should also disclose any conflict of interest.

References: The Vancouver system is required (see Br Med J 1971; 1: 532-551), with references numbered consecutively (included in parentheses) in text, and listed numerically with journal titles in NLM title abbreviation. List all the authors of cited paper when they are six or less; when seven and more, list three and add "et al." Attention to punctuation is required. References cited as being "in press" must have been accepted for publication, and the name of the journal included in the reference list. The authors are responsible for the accuracy of the references.

An example of the format of references for journal article is as follows:
Zurowski D, Dorbek L, Bugajski A, Thor PJ. The role of sensory C-fibers in response of afferent vagal stimulation. J Physiol Pharmacol 2008; 58(Suppl. 2): 179-190.

An example of the format for e-articles in press is as follows:
Targosz A, Brzozowski T, Pierzchalski P, et al. Helicobacter pylori promotes apoptosis, activates cyclooxygenase (COX)-2 and inhibits heat shock protein HSP70 in gastric cancer epithelial cells. Inflamm Res 2012; 2012: x. doi: 10.1007/s00011-012-0487-x.

An example of the format of references for a book is as follows:
Banks PA. Pancreatitis. New York, Plenum Medical, 1979.

An example of the format of references for contribution to a book is as follows:
Creutzfeldt W. Endocrine tumors of the pancreas. In The Diabetic Pancreas, BW Wolk, KF Mellman (eds). New York. Plenum Medical, 1977, pp. 551-590.

Figures and tables: Tables and figures should be submitted in separate files with a minimum resolution of 300 dpi. They should be referred in the text by arabic numerals, e.g. Table 3, Fig. 1. Colour figures in the Journal online are free, but there is charge of 80 EUR or in Polish currency 400 PLN for each colour figure in the printed version. Those Authors wishing to have figures in colour online but black and white in print must submit both colour and black and white versions of the figures with legends applicable to both versions of the figures, i.e. contain no mention of colour. Supplementary materials/figures are not accepted.

Abbreviations: The Authors should avoid abbreviations unless they are easily understood and help in reading the paper. The abbreviations that are well known in the field, do not need to be defined. All other abbreviations should be defined in the list of abbreviations.

SI units: All measurement except blood pressures are expressed in SI units.

PERMISSIONS
the Authors are responsible for obtaining permission to reproduce or adapt material protected by copyright, such as illustrations, photographs, tabular material, and quotations of substantial length. Letters of permission from the copyright holder and the author of the original source (with the complete bibliographic information) must be submitted with the manuscript.

Upon acceptance of a manuscript, the authors transfer all copyright to the Journal of Physiology and Pharmacology and neither whole published manuscripts, nor any part of it may be published elsewhere without written permission from Journal of Physiology and Pharmacology.

EDITORIAL AND REVIEWING PROCEDURE
All categories of papers are subjected to the same peer-review procedure. Manuscripts that are received for consideration are first examined by the editors of the Journal. Papers out of scope and with insufficient priority for publication are rejected promptly. The remaining papers are subjected to anonymous evaluations by two or three independent reviewers. Reviewers are given three weeks to complete their reviews. Authors have to submit revised manuscript within a designated period of time and it must contain the complete paper in two formats (first in Word with figures and tables in separate files and the second format in one pdf file with all figures and tables attached at the end of the text) and with itemized list of all changes made in response to each of the reviewer suggestions in the form of point-by-point letters, or a rebuttal to the comments made by each reviewer. Revised manuscript undergoes repeated evaluation by the same reviewers. The authors cannot enter into discussion with the editor with regards to papers that are rejected as being unsuitable for publication, and the editors decision of rejection is final. The authors whose papers have been accepted for publication will receive an e-mail message about the acceptance of their manuscripts for publication. The galley proof is in pdf file and will be e-mailed to them for making corrections, too. The substantial changes in proof will not be accepted.

PAYMENT
Payment for the author's fee should be made in EUR or in Polish zlotys (PLN), by bank transfer to the following bank account:

POLSKIE TOWARZYSTWO FIZJOLOGICZNE Zarzad Glowny, Bank PKO BP SA KRAKOW
Accout no: 13 1020 2892 0000 5902 0206 3261;
IBAN: PL 13102028920000590202063261;
SWIFT: B PKO PL PW.

Bank address is: PKO BANK POLSKI SA I ODDZIAL, 19/21 Wielopole Street, 30-942 KRAKOW, POLAND.

Payment by card or by the cash will not be accepted.
A manuscript-handling fee is 800 EUR or in Polish currency 3500 PLN, equivalent, and should be sent along with the manuscript submission. The fee is not refundable regardless of acceptance or rejection of the paper.


COPYRIGHT
This publication is copyrighted under the Berne Convention and the International Copyright Convention. All right reserved. Apart from any relaxations permitted under national copyright laws, no part of the publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means without the prior permission of the copyright owners.